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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2C All Species: 25.15
Human Site: S334 Identified Species: 46.11
UniProt: Q06413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06413 NP_002388.2 473 51221 S334 S A D L S S L S G F N T A S A
Chimpanzee Pan troglodytes XP_001139828 503 54271 S364 M L S L G Q V S A W Q Q H H L
Rhesus Macaque Macaca mulatta XP_001086412 483 52310 S344 S A D L S S L S G F N T A S A
Dog Lupus familis XP_858441 472 51065 S333 S A D L S S L S G F N T A S A
Cat Felis silvestris
Mouse Mus musculus Q8CFN5 474 51260 S334 S A D L S S L S G F N T A S A
Rat Rattus norvegicus Q2MJT0 495 53235 A356 G M L S L G Q A S A W Q Q H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510456 503 54885 S364 S A D L S S L S G F N T A S A
Chicken Gallus gallus Q9W6U8 499 53650 L360 N S P G M L S L G Q V S P W Q
Frog Xenopus laevis Q03413 498 54053 S349 S A D L A S L S T F S S P G S
Zebra Danio Brachydanio rerio NP_571387 465 49956 A325 G D L S S L S A F N S S A S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S382 T G S G G S S S S T S S N A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 I129 Q Q L Y H A L I T V R E R K E
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 V314 P A P V Q A M V H H L H Q L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.4 93.3 99.1 N.A. 98.7 56.5 N.A. 93 63.1 56.6 79.4 N.A. 32.4 N.A. N.A. N.A.
Protein Similarity: 100 74.3 94.8 99.3 N.A. 99.7 69.2 N.A. 94 74.1 70.4 88.5 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 0 N.A. 100 6.6 53.3 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 6.6 N.A. 100 26.6 80 40 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 36.7 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 0 0 8 16 0 16 8 8 0 0 47 8 39 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 47 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 47 0 0 0 0 0 % F
% Gly: 16 8 0 16 16 8 0 0 47 0 0 0 0 8 0 % G
% His: 0 0 0 0 8 0 0 0 8 8 0 8 8 16 8 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 8 24 54 8 16 54 8 0 0 8 0 0 8 16 % L
% Met: 8 8 0 0 8 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 8 39 0 8 0 8 % N
% Pro: 8 0 16 0 0 0 0 0 0 0 0 0 16 0 0 % P
% Gln: 8 8 0 0 8 8 8 0 0 8 8 16 16 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % R
% Ser: 47 8 16 16 47 54 24 62 16 0 24 31 0 47 16 % S
% Thr: 8 0 0 0 0 0 0 0 16 8 0 39 0 0 0 % T
% Val: 0 0 0 8 0 0 8 8 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _